MACPF/CDC proteins-- agents of defence, attack and invasion / Gregor Anderluh, Robert Gilbert, editors.

MACPF/CDC proteins-- agents of defence, attack and invasion /

This book focusses on evolutionary, structural and functional aspects of pore-forming proteins, bringing together prominent researchers in the fields of structural biology and cellular and biophysical techniques. The focus is on the MACPF/CDC protein super family that was originally discovered becau...

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Bibliographic Details
Other Authors: Anderluh, Gregor, 1969- (Editor), Gilbert, Robert (Editor)
Format: Electronic eBook
Language:English
Published: Dordrecht : Springer, 2014.
Series:Sub-cellular biochemistry ; v. 80.
Subjects:
Proteins.
Proteins > Biotechnology.
Cell membranes.
Electronic books.
Online Access: Full text (Wentworth users only)
Local Note:Ebook Library
Table of Contents:
  • Part I: Overview of MACPF/CDCs
  • Introduction: Brief Historical Overview
  • Distribution of MACPF/CDC proteins
  • Evolution of the Complement System
  • Part II: Structures of MACPF/CDCs
  • Structural Features of Cholesterol Dependent Cytolysins and Comparison to other MACPF-domain containing proteins
  • Perfringolysin O Structure and Mechanism of Pore Formation as a Paradigm for Cholesterol-Dependent Cytolysins
  • Structural Biology of the Membrane Attack Complex
  • Part III: Functional aspect
  • Membrane Interactions and Cellular Effects of MACPF/CDC Proteins
  • The Biology of Pneumolysin
  • Multifaceted Activity of Listeriolysin O, the Cholesterol-Dependent Cytolysin of Listeria monocytogenes
  • Perforin
  • a Key Pore-Forming Protein for Immune Control of Viruses and Cancer
  • Perforin and Human Diseases
  • The role of MACPF Proteins in the Biology of Malaria and other Apicomplexan Parasites
  • Chlamydial MACPF Protein CT153
  • Fungal MACPF-Like Proteins and Aegerolysins: Bi-Component Pore-Forming Proteins?
  • Fluorescence Imaging of MACPF/CDC Proteins: New Techniques and Their Application.

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