Neonatal neural rescue : a clinical guide /

"Worldwide more than one million babies die annually from perinatal asphyxia and its associated complications such as neonatal encephalopathy - one of the major causes of cerebral palsy and cognitive deficiencies in children aside from prematurity. Cooling the head - or the entire body - minimi...

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Bibliographic Details
Other Authors: Edwards, David, 1952-, Azzopardi, Denis V., Gunn, Alistair J.
Format: Electronic eBook
Language:English
Published: Cambridge : Cambridge University Press, 2013.
Series:Cambridge medicine.
Subjects:
Online Access: Full text (Wentworth users only)
Local Note:ProQuest Ebook Central
Table of Contents:
  • Scientific background
  • Neurological outcome after perinatal asphyxia at term
  • Molecular mechanisms of neonatal brain injury and neural rescue
  • The discovery of hypothermic neural rescue therapy for perinatal hypoxic-ischaemic encephalopathy
  • Clinical trials of hypothermic neural rescue
  • Economic evaluation of hypothermic neural rescue
  • Clinical neural rescue
  • Challenges for parents and clinicians discussing neuroprotective treatments
  • The pharmacology of hypothermia
  • Selection of infants for hypothermic neural rescue
  • Hypothermia during patient transport
  • Whole body cooling for therapeutic hypothermia
  • Selective head cooling
  • Hypothermic neural rescue for neonatal encephalopathy in mid- and low-resource settings
  • Cerebral function monitoring and EEG
  • Magnetic resonance imaging in hypoxic-ischaemic encephalopathy and the effects of hypothermia
  • Novel uses of hypothermia
  • Neurological follow-up of infants treated with hypothermia
  • Registry surveillance after neuroprotective treatment
  • The future
  • Novel neuroprotective therapies
  • Combining hypothermia with other therapies for neonatal neuroprotection
  • Biomarkers for studies of neuroprotection in infants with hypoxic ischaemic encephalopathy.